NCDCbioinformatics is the public bioinformatics software profile of the National Cancer Data Center. The account is organized around two major development tracks:
CURE-NGS: a panel-based genomic data construction and harmonization framework for heterogeneous clinical sequencing outputsK-CORE: analysis portal development for clinico-omics integration, visualization, and research-facing data exploration
CURE-NGS is the publication-facing framework for panel-based genomic data harmonization, transformation, and reproducible mutation annotation workflows.
| Repository | Purpose |
|---|---|
| cure-ngs-panel-harmonization-framework | Umbrella repository for the manuscript, editorial declarations, and framework metadata |
| panel_VCF_vcf2maf_pipeline | Multi-panel VCF preprocessing, build harmonization, and VCF-to-MAF conversion |
| HGVS_to_minimal_MAF_pipeline | HGVS-driven minimal MAF generation pipeline |
| minimal_MAF_to_annotated_MAF_pipeline | Minimal-MAF-to-annotated-MAF conversion pipeline |
| gene_name_harmonization | Gene symbol harmonization utility |
| gene_fusion_normalizer | Fusion gene normalization utility |
| hgvs_normerlizer | HGVS nomenclature normalization utility |
K-CORE represents the clinico-omics analysis portal development track, including backend services, frontend visualization, and synthetic demonstration resources. The repositories below are mirrored under this profile for unified public presentation while the original K-CORE-NCDC organization remains unchanged.
| Repository | Area | Summary |
|---|---|---|
| K-CORE-NCDC | Portal overview | Landing repository for the mirrored K-CORE portal software collection |
| ncc-backend | Backend platform | Django-based backend source structure for K-CORE portal services and clinico-omics workflows |
| ncc-frontend | Frontend visualization | React-based portal UI source structure for clinico-omics exploration and visual analytics |
| synthetic-data-set | Demonstration data | Representative synthetic dataset package used for portal validation and demonstration |
- Panel-based genomic data construction and harmonization
- Provenance-aware transformation of VCF, HGVS, and report-derived inputs
- Research-ready mutation annotation workflows
- Clinico-omics portal engineering and interactive data visualization
- Terminology normalization for cancer genomics data integration
- Institution: National Cancer Data Center
- Website: www.cancerdata.re.kr
- Location: Goyang-si, Gyeonggi-do, Republic of Korea
The repositories under this profile are intended for research software and framework documentation. Patient-level clinical or genomic data are not distributed through this profile.