Simultaneous cortico-spinal fMRI (CoSpine) Pain-dataset

Version: v1.1.0
Date: 2025-06-19
BIDS-compliant

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1. Dataset overview

This is the first open-access, BIDS-compliant cortico-spinal task-based fMRI dataset. It enables exploration of cortical and spinal responses to thermal pain in healthy adults by providing simultaneous brain-and-spinal fMRI, physiological recordings, and behavioural ratings.

• Task: 4 s thermal pain stimuli followed by self-report ratings
• Modalities: fMRI (task-pain BOLD), T1-weighted structural MRI, field maps (GRE magnitude/phase, reversed phase-encoding B0), physiological signals (pulse & respiration), events/behavioural logs
• Subjects: 39

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2. Experimental design

• Pain stimulus: contact thermode, temperatures 42–47 °C (subject-specific)
• Ratings:
  • PR – pain intensity (0–10 VAS)
  • UpR – unpleasantness (0–10 VAS)

Full stimulus & rating onset/duration are recorded in each *_events.tsv.

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3. Data acquisition

• Scanner: 3 T Siemens Prisma (Erlangen, Germany)
• Coil: Standard 64-channel head-neck coil

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4. Dataset structure

dataset/
├── dataset_description.json
├── README
├── task-pain_events.json
├── participants.tsv + .json
├── sub-01
│   ├── anat
│   │   ├── sub-01_T1w.json
│   │   └── sub-01_T1w.nii.gz
│   ├── fmap
│   │   ├── sub-01_acq-GRE_magnitude1.json
│   │   ├── sub-01_acq-GRE_magnitude1.nii.gz
│   │   ├── sub-01_acq-GRE_magnitude2.json
│   │   ├── sub-01_acq-GRE_magnitude2.nii.gz
│   │   ├── sub-01_acq-GRE_phase1.json
│   │   ├── sub-01_acq-GRE_phase1.nii.gz
│   │   ├── sub-01_dir-AP_epi.json
│   │   ├── sub-01_dir-AP_epi.nii.gz
│   │   ├── sub-01_dir-PA_epi.json
│   │   └── sub-01_dir-PA_epi.nii.gz
│   └── func
│       ├── sub-01_task-pain_bold.json
│       ├── sub-01_task-pain_bold.nii.gz
│       ├── sub-01_task-pain_dicom001_anonymized.IMA
│       ├── sub-01_task-pain_events.tsv
│       ├── sub-01_task-pain_recording-pulse_physio.json
│       ├── sub-01_task-pain_recording-pulse_physio.tsv.gz
│       ├── sub-01_task-pain_recording-respiratory_physio.json
│       └── sub-01_task-pain_recording-respiratory_physio.tsv.gz
├── derivatives/
│   └── preprocessed/
│       ├── dataset_description.json
│       └── sub-01/

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5. Column & label definitions

*_events.tsv

Column	Description
trial_type	pain = heat stimulus, rating = VAS response period
PR	Pain intensity (0–10)
UpR	Unpleasantness (0–10)

participants.tsv

Column	Units
age	years
sex	m / f
education	years
heat_temperature	°C

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6. Quality control / preprocessing

• Structural images have been defaced to protect participant identity.
• Optimized preprocessing pipeline applied using:
  • FSL 6.0.7
  • Spinal Cord Toolbox 5.9

Includes distortion correction (TOPUP) and physiological noise correction.
Preprocessed data available in derivatives/preprocessed/.

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Contact

• Zhaoxing Wei – zhaoxing.wei@dartmouth.edu
• Yazhuo Kong – kongyz@psych.ac.cn