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Version 4.0.0

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@xiao-chen-xc xiao-chen-xc released this 29 May 16:14
324b00e

Summary of changes:

  • Rewrite Paraphase in Rust. Switch to Rust binary release.
  • Remove the -l option. Paraphase now only accepts a single BAM file as input.
  • No change in output file formats except that region-specific information, i.e. fields that are not computed for every region, is now reported under the region_specific_info field in the JSON output. See docs/json.md for more details.
  • Add a small algorithm change for more stringent depth-based copy number adjustment, requiring a high depth signal for calling a haplotype as present in two copies when considering uniquely supporting as well as non-uniquely supporting reads (only using uniquely supporting reads in previous versions).
  • Changes in target regions: Add pms2 to chm13 config and CATSPER2 to hg38 config