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Pangenome#14

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DonFreed merged 19 commits intodevfrom
pangenome
Aug 21, 2025
Merged

Pangenome#14
DonFreed merged 19 commits intodevfrom
pangenome

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Initial implementation of a pangenome pipeline.

DonFreed added 19 commits August 7, 2025 15:14
Updates to the pangenome pipeline:
- Output a deduped CRAM file
- Reduce kmc default memory to 58g
- Remove the indel realignment step
- Add the `IndelLeftAlignReadTransform` read filter
- Update the `estimate_ploidy.py` script to handle multiple input bams
* Use the new `.hdr` functionality to strip contig prefixes.
* Use `--into-paths <paths.dict>` argument in `vg surject` instead of
 `--into-ref GRCh38` to control the contig order.
@DonFreed DonFreed merged commit 1e44e00 into dev Aug 21, 2025
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@DonFreed DonFreed deleted the pangenome branch August 21, 2025 16:34
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