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PEN-ASSEMBLE v0.5.0

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@github-actions github-actions released this 20 May 10:52
· 25 commits to main since this release

PEN-ASSEMBLE v0.5.0

IS110-family bridge recombinase design pipeline.

Results summary (v0.5.0)

  • 1,029 designs scored across 4 strategies (A–D)
  • 16 designs beat IS621 verbatim lockpoint (PenScore > 0.929)
  • 5/5 pre-registered predictions PASS"PUBLISH with strong claim"
  • Top design: IS621_deimmunized_v2 (PenScore = 0.9673)

Install

pip install pen-assemble==v0.5.0

See README.md and catalog/release_v0.5.0/ for the full design catalog.