This happened to me several times. If I forget to plug in my laptop for the night and it dies, everything is fine when I boot up, except two Chromium extensions lose their entire configuration - one of those is ScriptSafe. It's also happened at least once when Chromium was killed with sigterm. All other extensions retained their configs.
It would be great if ScriptSafe was more resilient to this.
I'm using ScriptSafe with Chromium, currently 65.0.3325.181, on Linux.
PS. Thanks a lot for your work on ScriptSafe - it's a must have, as far as I'm concerned, along with uBlock Origin, HTTPS Everywhere and Privacy Badger.