This is a curated list of academic papers and articles about ME/CFS. The key objectives here are:
- have a central and starting point for those looking for more information about this medical condition;
- receive your help and contribution by suggesting new papers or scientific articles.
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- ME/CFS Research: Ron Davis's (Professor of Biochemistry & Genetics, and Director of the Stanford Genome Technology Center at Stanford University) Talk at Albert Einstein College of Medicine https://www.youtube.com/watch?v=lHY1Q232HsM&t=1208s
(preprint!)Bragée, B., Michos, A., Fahlgren, M., Drum, B., Szulkin, R., & Bertilson, B. C. (2019, November 27). Bragee Bertilson et al. - ME CFS and Intracranial Hypertension. https://doi.org/10.31219/osf.io/qwn5h- Mueller C, Lin JC, Sheriff S, Maudsley AA, Younger JW. Evidence of widespread metabolite abnormalities in Myalgic encephalomyelitis/chronic fatigue syndrome: assessment with whole-brain magnetic resonance spectroscopy. Brain Imaging Behav. 2020;14(2):562-572. https://doi.org/10.1007/s11682-018-0029-4
- Słomko, J.; Estévez-López, F.; Kujawski, S.; Zawadka-Kunikowska, M.; Tafil-Klawe, M.; Klawe, J.J.; Morten, K.J.; Szrajda, J.; Murovska, M.; Newton, J.L.; Zalewski, P., on behalf of the European Network on ME/CFS (EUROMENE); Autonomic Phenotypes in Chronic Fatigue Syndrome (CFS) Are Associated with Illness Severity: A Cluster Analysis. J. Clin. Med. 2020, 9, 2531. https://doi.org/10.3390/jcm9082531
- Tölle, M.; Freitag, H.; Antelmann, M.; Hartwig, J.; Schuchardt, M.; van der Giet, M.; Eckardt, K.-U.; Grabowski, P.; Scheibenbogen, C. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Efficacy of Repeat Immunoadsorption. J. Clin. Med. 2020, 9, 2443. https://doi.org/10.3390/jcm9082443
- Lande, A., Fluge, Ø., Strand, E.B. et al. Human Leukocyte Antigen alleles associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Sci Rep 10, 5267 (2020). https://doi.org/10.1038/s41598-020-62157-x
- Discussion: The best evidence yet that immune system problems can cause ME/CFS? https://mecfsresearchreview.me/2020/04/23/the-best-evidence-yet-that-immune-system-problems-can-cause-me-cfs/
- Milivojevic M, Che X, Bateman L, Cheng A, Garcia BA, et al. (2020) Plasma proteomic profiling suggests an association between antigen driven clonal B cell expansion and ME/CFS. PLOS ONE 15(7): e0236148. https://doi.org/10.1371/journal.pone.0236148
- Maksoud R, du Preez S, Eaton-Fitch N, Thapaliya K, Barnden L, et al. (2020) A systematic review of neurological impairments in myalgic encephalomyelitis/ chronic fatigue syndrome using neuroimaging techniques. PLOS ONE 15(4): e0232475. https://doi.org/10.1371/journal.pone.0232475
(preprint!)Rodriguez, Lucie S.T.; Pou, Christian et al. Achieving symptom relief in patients with Myalgic encephalomyelitis by targeting the neuro-immune interface and inducing disease tolerance bioRxiv. https://doi.org/10.1101/2020.02.20.958249(TRIAL - last update: July 15th, 2020)The Exercise Response to Pharmacologic Cholinergic Stimulation in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome https://clinicaltrials.gov/ct2/show/NCT03674541- Discussion: The Mestinon Clinical Trial for ME / CFS https://www.omf.ngo/2020/04/26/the-mestinon-clinical-trial-for-me-cfs/
- Kashi, A.A.; Davis, R.W.; Phair, R.D. The IDO Metabolic Trap Hypothesis for the Etiology of ME/CFS. Diagnostics 2019, 9, 82. https://doi.org/10.3390/diagnostics9030082
- Saha, Amit K., Schmidt, Brendan R. et al. Red blood cell deformability is diminished in patients with Chronic Fatigue Syndrome. Clinical Hemorheology and Microcirculation, vol. 71, no. 1, pp. 113-116, 2019. https://doi.org/10.3233/CH-180469
- R. Esfandyarpour, A. Kashi, et al. A nanoelectronics-blood-based diagnostic biomarker for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Davis Proceedings of the National Academy of Sciences May 2019, 116 (21) 10250-10257. https://doi.org/10.1073/pnas.1901274116
- Discussion:
- Latest from Ron Davis: more evidence of “something in the blood” https://mecfsresearchreview.me/2019/12/10/latest-from-ron-davis-more-evidence-of-something-in-the-blood/
- Biomarker for chronic fatigue syndrome identified https://www.med.stanford.edu/news/all-news/2019/04/biomarker-for-chronic-fatigue-syndrome-identified.html
- Threading the Needle: Nanoneedle Scores Big in First ME/CFS Test https://www.healthrising.org/blog/2019/05/07/threading-the-needle-nanoneedle-scores-big-in-first-me-cfs-test/
- Discussion:
- Rowe PC, Marden CL, Heinlein S, Edwards CC 2nd. Improvement of severe myalgic encephalomyelitis/chronic fatigue syndrome symptoms following surgical treatment of cervical spinal stenosis. J Transl Med. 2018;16(1):21. Published 2018 Feb 2. https://doi.org/10.1186/s12967-018-1397-7
- Giloteaux, L., Goodrich, J.K., Walters, W.A. et al. Reduced diversity and altered composition of the gut microbiome in individuals with myalgic encephalomyelitis/chronic fatigue syndrome. Microbiome 4, 30 (2016). https://doi.org/10.1186/s40168-016-0171-4
- Nakatomi Y, Mizuno K, Ishii A, et al. Neuroinflammation in Patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: An ¹¹C-(R)-PK11195 PET Study. J Nucl Med. 2014;55(6):945-950. https://doi.org/10.2967/jnumed.113.131045