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compressing-chemistry

Code for discovering compressing substructures from a dataset of chemicals. The MML87_multiprocessing.py file runs a greedy search procedure which finds the maximally compressing substructure at each iteration, and adds it to a list. The search continues until no further substructure can be found which further compresses the data. We use the Minimum Message Length principle to calculate the amount that a set of substructures compresses the dataset.

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The CHEMBL_36 file is too large to upload. One may use the .sdf file found at the official CHEMBL website.

To run the algorithm, run: python MML87_multiprocessing.py

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Code to reproduce results from https://www.arxiv.org/abs/2511.05728

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