SpliceCraft v1.0.31

New features

• Ribosome-binding-site strength prediction + design (E. coli), built in. SpliceCraft can now estimate how strongly a ribosome binding site drives translation, and reverse-design a 5′UTR (Shine-Dalgarno + spacer) to hit a target strength — pure Python, no external library. It's a biophysical model on top of the new RNA folder/cofold: it weighs the SD : anti-SD match, the 5′UTR structure that hides the site, the spacing to the start codon, and the start codon itself. Strengths are relative — ideal for tuning one gene against another (the operon use case), not an absolute rate. Available through the agent API: rbs-strength (predict), design-rbs (reverse-design to a target), and cofold-rna (heterodimer ΔG, e.g. an anti-SD : mRNA hybrid). The foundation for the operon expression-tuning tools coming next.