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New locus: CPUM_TYMS#212

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hdashnow merged 7 commits intomainfrom
CPUM
Jul 1, 2025
Merged

New locus: CPUM_TYMS#212
hdashnow merged 7 commits intomainfrom
CPUM

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@hdashnow
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@hdashnow hdashnow commented Jun 27, 2025

Description

This is the same content as in #204 by @Macayla-weiner, except I've rebased it against main so that it should include a better website preview, including properly formatted references.

Replaces: #204
Fixes: #200

Major Changes

  • New locus: CPUM_TYMS

Checklist

  • All changes are well summarized
  • Check all tests pass
  • Check that the website preview looks good
  • Update the STRchive version in CITATION.cff, format X.Y.Z. If any major changes, increment Y. If only minor changes, increment Z. If the breaking change (rare), increment X.
  • Ask someone to review this PR

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@hdashnow
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@Macayla-weiner would you like to try adding to this PR by editing the CPUM branch within the dashnowlab repository?

There are still a few suggestions left from here #204 (review)

@hdashnow hdashnow requested a review from Macayla-weiner June 27, 2025 05:39
@hdashnow hdashnow mentioned this pull request Jun 27, 2025
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Macayla-weiner and others added 3 commits July 1, 2025 16:14
Edited the disease description and details.

Update data

trimming T2T start coordinates by 19 bp to start at first perfect motif GATGGT
Change the representation of MUC1 from a homopolymer expansion to a VNTR
motif switch

Fixes: # **Link to any relevant issues and/or discussions**

- Change the representation of MUC1 from a homopolymer expansion to a
VNTR motif switch

- Don't plot loci with all missing data in locus plots

- [x] All changes are well summarized
- [x] Check all tests pass
- [x] Check that the website preview looks good
- [ ] Update the STRchive version in `CITATION.cff`, format X.Y.Z. If
any major changes, increment Y. If only minor changes, increment Z. If
the breaking change (rare), increment X.
- [x] Ask someone to review this PR

---------

Co-authored-by: hdashnow <3794821+hdashnow@users.noreply.github.com>
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hdashnow commented Jul 1, 2025

I edited the T2T start coordinate a little so that it starts at the first perfect motif. And rebased against main so it can merge.

@hdashnow hdashnow merged commit c2451e4 into main Jul 1, 2025
1 check passed
@hdashnow hdashnow deleted the CPUM branch July 1, 2025 22:50
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New Locus in TYMS?

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