Brain MRI Collections (after 2020)

Curated external human brain diffusion MRI datasets released after ~2020, sourced from public archives (e.g., Dryad, Zenodo, ScienceDB).
Datasets are provided as-is and intended for:

• Research and method development
• Tractography benchmarking
• Diffusion modeling (DTI, HARDI, NODDI, SMT/SANDI)
• Test–retest studies
• Educational use

All datasets retain their original license, citation, and usage terms required by data owners.
Always cite the original dataset DOIs.

---

Releases in This Repository

---

1) Ex vivo Mesoscale Human Temporal Lobe Dataset (pitt-hippo)

Mesoscale ex vivo diffusion MRI of the human temporal lobe, emphasizing hippocampal lamellar and fimbria pathways.

Download command

curl -s https://api.github.com/repos/data-hcp/brain-after-2020/releases/tags/pitt-hippo | jq -r '.assets[].browser_download_url' | xargs -n1 -P4 curl -LO

(Invoke-RestMethod "https://api.github.com/repos/data-hcp/brain-after-2020/releases/tags/pitt-hippo").assets | ForEach-Object { Invoke-WebRequest $_.browser_download_url -OutFile (Split-Path $_.browser_download_url -Leaf) }

Summary: Ex vivo dMRI at 250 µm isotropic (upsampled to 125 µm). Reconstruction using GQI. Includes hippocampal subfields (CA1–3, DG), head–body–tail regions, fimbria ROIs, and 50+ dissected pathway templates.

License: Public domain (Dryad)
DOI: https://doi.org/10.5061/dryad.jh9w0vtnq

---

2) Brain and Spinal Cord Multi-Shell Diffusion MRI (vu-brain-cord)

Integrated brain + cervical spinal cord multi-shell dMRI for 11 subjects (6 with test–retest), fully BIDS-compliant.

Download command

curl -s https://api.github.com/repos/data-hcp/brain-after-2020/releases/tags/vu-brain-cord | jq -r '.assets[].browser_download_url' | xargs -n1 -P4 curl -LO

(Invoke-RestMethod "https://api.github.com/repos/data-hcp/brain-after-2020/releases/tags/vu-brain-cord").assets | ForEach-Object { Invoke-WebRequest $_.browser_download_url -OutFile (Split-Path $_.browser_download_url -Leaf) }

Derived datasets include NODDI, SMT, SANDI, and DTI model fits, segmentations, FreeSurfer reconstructions, reverse-PE scans, and BIDS metadata.

License: CC BY 4.0
DOI: https://doi.org/10.5281/zenodo.15512428

---

3) EDEN2020 Human Brain MRI Datasets (vssru-eden2020)

High-resolution multimodal MRI (T1, FLAIR, SWI, DTI, NODDI) from 15 healthy adults, collected to support neurosurgical imaging research.

Download command

curl -s https://api.github.com/repos/data-hcp/brain-after-2020/releases/tags/vssru-eden2020 | jq -r '.assets[].browser_download_url' | xargs -n1 -P4 curl -LO

(Invoke-RestMethod "https://api.github.com/repos/data-hcp/brain-after-2020/releases/tags/vssru-eden2020").assets | ForEach-Object { Invoke-WebRequest $_.browser_download_url -OutFile (Split-Path $_.browser_download_url -Leaf) }

Includes angiographic, HARDI, and white matter microstructure imaging; derived DTI/NODDI maps; probabilistic tractography.

License: CC BY-NC-ND 4.0
DOI: https://doi.org/10.5281/zenodo.3994749

---

4) Structural & Functional Basis of Neuronal Plasticity — Healthy Controls (vitality)

Multimodal MRI for studying CBF, CMRO₂, DWI, task-induced plasticity, and metabolic responses.

Download command

curl -s https://api.github.com/repos/data-hcp/brain-after-2020/releases/tags/vitality | jq -r '.assets[].browser_download_url' | xargs -n1 -P4 curl -LO

(Invoke-RestMethod "https://api.github.com/repos/data-hcp/brain-after-2020/releases/tags/vitality").assets | ForEach-Object { Invoke-WebRequest $_.browser_download_url -OutFile (Split-Path $_.browser_download_url -Leaf) }

Includes MP2RAGE, pCASL DEXI perfusion scans, two DWIs, TRUST/IR-EPI metabolic sequences, task behavioral traces.

License: CC BY 4.0
Source: https://zenodo.org/records/15149088

---

5) In Vivo Whole-Brain Connectom dMRI at 760 µm (mgh-760)

Ultra-high-resolution Connectom dMRI with 1260 directions, 18 hours of acquisition.

Download command

curl -s https://api.github.com/repos/data-hcp/brain-after-2020/releases/tags/mgh-760 | jq -r '.assets[].browser_download_url' | xargs -n1 -P4 curl -LO

(Invoke-RestMethod "https://api.github.com/repos/data-hcp/brain-after-2020/releases/tags/mgh-760").assets | ForEach-Object { Invoke-WebRequest $_.browser_download_url -OutFile (Split-Path $_.browser_download_url -Leaf) }

Includes submillimeter structural MRI, field maps, acquisition logs, and preprocessing scripts.

License: CC0
DOI: https://doi.org/10.5061/dryad.rjdfn2z8g

---

6) Imaging Chinese Young Brains – CHIMGEN Subset (icyb)

Large-sample multimodal dataset of 215 young Chinese adults with T1, rs-fMRI, DTI, and ASL.

Download command

curl -s https://api.github.com/repos/data-hcp/brain-after-2020/releases/tags/icyb | jq -r '.assets[].browser_download_url' | xargs -n1 -P4 curl -LO

(Invoke-RestMethod "https://api.github.com/repos/data-hcp/brain-after-2020/releases/tags/icyb").assets | ForEach-Object { Invoke-WebRequest $_.browser_download_url -OutFile (Split-Path $_.browser_download_url -Leaf) }

Includes BIDS-structured data with defaced anatomical scans and MRI-QC reports.

License: CC BY 4.0
DOI: https://doi.org/10.11922/sciencedb.00740

---

7) Functional & Structural MRI After tSMS Stimulation (cinac-tsms)

Double-blind crossover experiment comparing real vs sham tSMS over right M1.

Download command

curl -s https://api.github.com/repos/data-hcp/brain-after-2020/releases/tags/cinac-tsms | jq -r '.assets[].browser_download_url' | xargs -n1 -P4 curl -LO

(Invoke-RestMethod "https://api.github.com/repos/data-hcp/brain-after-2020/releases/tags/cinac-tsms").assets | ForEach-Object { Invoke-WebRequest $_.browser_download_url -OutFile (Split-Path $_.browser_download_url -Leaf) }

Includes multiecho resting-state fMRI, DWI, corrected phase images, and defaced anatomy.

License: CC BY 4.0
DOI: https://doi.org/10.5281/zenodo.15224957

---

8) B-Q Minded Test–Retest Cross-Scanner Dataset (bqminded)

Test–retest dataset for cross-scanner qMRI and diffusion harmonization (Skyra 3T vs PrismaFit 3T).

Download command

curl -s https://api.github.com/repos/data-hcp/brain-after-2020/releases/tags/bqminded | jq -r '.assets[].browser_download_url' | xargs -n1 -P4 curl -LO

(Invoke-RestMethod "https://api.github.com/repos/data-hcp/brain-after-2020/releases/tags/bqminded").assets | ForEach-Object { Invoke-WebRequest $_.browser_download_url -OutFile (Split-Path $_.browser_download_url -Leaf) }

Used in recent harmonization studies (NeuroCombat, LongCombat). Includes anatomical and diffusion MRI.

License: CC BY 4.0
DOI: https://doi.org/10.5281/zenodo.6473268

---

Licensing & Attribution

Each dataset retains its original license. Use must comply with:

• CC0 / CC BY
• CC BY-NC / CC BY-NC-ND
• Dataset-specific restrictions

Cite:

1. The dataset DOI
2. The primary research article (if applicable)
3. Optionally:
   “Data access facilitated by the data-hcp/brain-after-2020 repository.”

---

Intended Use

• Diffusion modeling (DTI, HARDI, NODDI, SMT/SANDI)
• High-resolution tractography
• Test–retest analyses
• Cross-scanner harmonization
• Educational teaching sets for MRI & connectomics

---

Notes

• Some datasets include partial acquisitions or subject-specific issues; see their notes.
• Derived files (FIB, SRC, microstructural maps) reflect specific pipelines.
• Some datasets include only derivatives, not original raw DICOM/NIfTI.