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CBN18-ENABLE - Enabling Neuroscience research Approaches for Brain, feeLings and Emotions

Dr. Benicio Frey, Dr. Pierre Blier, Dr. Faranak Farzan, Dr. Jane Foster, Dr. Raymond Lam MD, Dr. Roumen Milev, Dr. Daniel Müller, Dr. Sagar Parikh, Dr. Claudio Soares, Dr. Valerie Taylor, Dr. Gustavo Turecki, Dr. Rudolf Uher, Dr. Joshua Rosenblat, Dr. Nicholas Bock, Dr. Nathan Churchill, Dr. Lena Quilty, Dr. Stefan Kloiber, Dr. Ishrat Husain, Dr. Kate Harkness, Dr. Abraham Nunes, Dr. Katharine Dunlop and the CAN-BIND Study Team

Overview

More than 350 million people worldwide live with depression and bipolar disorders, yet finding the right treatment often involves trial and error. Advancing precision psychiatry requires large, standardized datasets that reflect real-world populations.

The Enabling Neuroscience research Approaches for Brain, feeLings and Emotions (ENABLE) was developed in partnership with patients and supported by the CAN-BIND Network, Brain Canada and the Ontario Brain Institute.

The baseline release will include data from over 400 participants with major depressive disorder and bipolar disorder across nine sites in Canada. Available datasets will include structural MRI neuroimaging, clinical and psychiatric history, demographics (including sex, age, gender diversity, and socioeconomic status), patient health questionnaires, work and social adjustment scales, quality-of-life indicators, Structured Clinical Interviews for DSM Disorders (SCID), and the Quick Inventory of Depressive Symptomatology (QIDS).

Data organization

Data is organized into packages by Treatment Group (ENABLE), Imaging Scan Type, and Clinical Data Collection Domain.

Access information

To gain access to Brain-CODE Controlled Data Release data, Study Investigators will submit requests via Data Release Portals at www.braincode.ca. These requests will be reviewed by the Brain-CODE Data Access Committee and the Brain-CODE Steering Committee. Learn more about these Committees in the Brain-CODE Governance Policy (https://braininstitute.ca/docs/Brain-CODE-Governance-Policy-version-FINAL.pdf). "

Visit the Brain-CODE Knowledge Base to learn more about our data releases.

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