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New Pyrogenic Threshold and MSP1 Antibody Fix

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@stitova-idm stitova-idm released this 12 Jan 23:58
· 56 commits to main since this release

InnateImmuneVariationType:
NONE
PYROGENIC_THRESHOLD
PYROGENIC_THRESHOLD_VS_AGE_CONCAVE <-- formerly PYROGENIC_THRESHOLD_VS_AGE
PYROGENIC_THRESHOLD_VS_AGE_INCREASING_AND_CYTOKINE_KILLING_INVERSE <-- new pyrogenic threshold logic

New parameters:
Pyrogenic_Threshold_Min - minimum below which person's pyrogenic threshold cannot be set. For example, if Pyrogenic_Threshold in configuration parameters is 1500, and person's innate immune variation coefficient is 0.01, but Pyrogenic_Threshold_Min is 1000 - that person's pyrogenic threshold will be set to 1000.
Pyrogenic_Threshold_Max - maximum above which person's pyrogenic threshold cannot be set. For example, if Pyrogenic_Threshold in configuration parameters is 1500, and person's innate immune variation coefficient is 10, but Pyrogenic_Threshold_Max is 2000 - that person's pyrogenic threshold will be set to 2000.

MSP1_Growth_Aligned - If true(1), the formula for calculating the MSP1 antibody capacity growth is aligned with the formula for calculating the PfEMP1 antibody capacity growth. If false(0), the original formula for calculating MSP1 antibody capacity growth is used. This is an optional parameter that gives us access to the fix for #140. You can run the code with or without the fix. The model needs to be re-calibrated for the fix as it changes the rate of growth.

For more info, please see emodpy-malaria documentaion