halfmarble is an open-source, strict "Glass Box" bioinformatics platform designed for the Parkinson's Disease (PD) community.
As a neurodegenerative data architecture, halfmarble is engineered to track deterministic Pharmacokinetic (PK) modeling against objective motor testing and continuous metabolic state.
In an era of dangerous algorithmic hallucinations in healthcare, halfmarble rejects the "black box." Every parameter, absorption curve, and metric traces directly to published, verifiable clinical science.
The software platform currently consists of functional web prototypes:
- SteadyDoseTracker: Deterministic Bateman absorption modeling for levodopa pharmacokinetics.
- SteadyFastingTracker: Metabolic window tracking aligned with neuro-compromised needs.
- SteadyFuelTracker: Engineered explicitly around Therapeutic Carbohydrate Restriction (TCR) protocols to track therapeutic nutritional ketosis.
halfmarble also builds dedicated hardware:
- SteadyHandTool: Open-source (CERN-OHL-S-2.0) high-mass tremor-dampening fixture for fine-motor work.
- UnSteadyRing: Wearable kinematic and biometric sensor system — ten passive chipless fractal-resonant rings excited by WiFi radio from two wrist-worn hubs that also capture single-lead ECG, PPG, and skin temperature. Provisional patent filed.
Patient data is not a commodity. Our privacy framework utilizes explicit, verifiable mathematical models:
k ≥ 50Anonymityε = 1.0Differential Privacy
halfmarble is not a startup; it is a patient-led R&D fight. The science is the engine—we just built the dashboard.
To ensure the underlying science continues to advance, we legally pledge a flat percentage of our software net profits to the institutions driving the vanguard of research:
- 2.5% to the Michael J. Fox Foundation (MJFF)
- 2.5% to the Public Health Collaboration (PHC UK)
For live prototypes and full clinical documentation, visit halfmarble.com.