Uncertainty and urgency: Tackling ME/CFS research and assessing the risk of SARS-CoV-2 Omicron subvariants in vaccinated populations
This repository holds the LaTeX code and documentation (figures, articles, and supplemental files) needed to compile the approved final verion of my PhD Thesis, titled "Uncertainty and urgency: Tackling ME/CFS research and assessing the risk of SARS-CoV-2 Omicron subvariants in vaccinated populations". The PDF file can be accessed here.
This PhD project was funded by Fundação para a Ciência e a Tecnologia (mixed grant reference SFRH/BD/149758/2019), and was produced at Instituto de Medicina Molecular João Lobo Antunes, Faculty of Medicine, University of Lisbon (host institution), and Faculty of Mathematics and Information Science, Warsaw University of Technology (international host institution). This thesis was defended on May 10th, 2024.
- Thank you to my supervisor and co-supervisor: Nuno Sepúlveda and Luís Graça
- Thank you to the members of my PhD thesis committee: Jorge Carneiro, Ruy Ribeiro, and Elsa Vieira de Sousa
- Thank you to the members of the jury: Karl Morten, Pedro Oliveira, Paulo Nogeira, and Miguel Prudêncio
- Thank you to the president of the public defense: Mário Ramirez
In descending chronological order:
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Association analysis between symptomology and herpesvirus IgG antibody concentrations in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and multiple sclerosis
T.D. Domingues, J. Malato, A.D. Grabowska, J.-S. Lee, J. Ameijeiras-Alonso, P. Biecek, L. Graça, H. Mouriño, C. Scheibenbogen, F. Westermeier, L. Nacul, J.M. Cliff, E. Lacerda, and N. Sepúlveda Heliyon 2023 
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Impact of misdiagnosis in case-control studies of myalgic encephalomyelitis/chronic fatigue syndrome
J. Malato, L. Graça, and N. Sepúlveda Diagnostics 2023 
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Stability of hybrid versus vaccine immunity against BA.5 infection over 8 months
J. Malato, R.M. Ribeiro, E. Fernandes, P.P. Leite, P. Casaca, C. Antunes, V.R. Fonseca, M.C. Gomes, and L. Graca The Lancet Infectious Diseases 2023 00833--7-blue){kind=icon}
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Risk of BA.5 infection among persons exposed to previous SARS-CoV-2 variants
J. Malato, R.M. Ribeiro, P.P. Leite, P. Casaca, E. Fernandes, C. Antunes, V.R. Fonseca, M.C. Gomes, and L. Graca New England Journal of Medicine 2022 
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Impact of misclassification and imperfect serological tests in association analyses of ME/CFS applied to COVID-19 data
J. Malato, L. Graça, and N. Sepúlveda Springer Proceedings in Mathematics & Statistics 2022 
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Revisiting IgG Antibody Reactivity to Epstein-Barr Virus in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Its Potential Application to Disease Diagnosis
N. Sepúlveda, J. Malato, F. Sotzny, A.D. Grabowska, A. Fonseca, C. Cordeiro, L. Graça, P. Biecek, U. Behrends, J. Mautner, F. Westermeier, E.M. Lacerda, and C. Scheibenbogen Frontiers in Medicine 2022 
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Statistical challenges of investigating a disease with a complex diagnosis
J. Malato, L. Graça, L. Nacul, E. M. Lacerda, and N. Sepúlveda Portuguese Statistical Society Proceedings 2021 
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The SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) in myalgic encephalomyelitis/chronic fatigue syndrome: A meta-analysis of public DNA methylation and gene expression data
J. Malato, F. Sotzny, S. Bauer, H. Freitag, A. Fonseca, A.D. Grabowska, L. Graça, C. Cordeiro, L. Nacul, E.M. Lacerda, J. Castro-Marrero, C. Scheibenbogen, F. Westermeier, and N. Sepúlveda Heliyon 2021 
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