AltEx-BE ver1.1.0 release

AltEx-BE version 1.1.0 release

• This release fixes inconsistencies around off-target counting and strand interpretation, improving result reliability across the pipeline.

Highlights

• Improved reverse-complement handling in offtarget_scorer.py
  - Added support for extended IUPAC bases (R/Y/S/W/K/M/B/V/D/H/N)
• Refined off-target counting flow
  - Aligned logic with actual sequence (sgrna_sequence) handling
  - Kept reverse-complement matches included in final counts
• Fixed sgrna_strand derivation in output_formatter.py
  - Strand inferred from sgrna_target_sequence is now flipped when gene strand is
  -, so output is genome-oriented
• Updated script/run_with_all_genes.py
  - Added outputs for formatted exploded results and off-target-scored results in
  all-genes runs
• Tests updated
  - Added/adjusted tests for output_formatter and offtarget_scorer to reflect the
  corrected behavior

Impact

• sgrna_strand now reflects genome orientation more accurately.
• Existing result artifacts (including offtarget_statistics.csv) should be
  regenerated with this release for consistency with the new logic.