0.1.12-alpha
Pre-release
Pre-release
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3102 commits
to master
since this release
This release contains some bug fixes and performance improvements:
Improvements
- Thread management has been improved; there is now a dedicated VCF writing thread, and tasks can be run as soon as they are created, rather than having to wait for all tasks on a contig to be made.
- A new de novo mutation model has been introduced which reduces false positive indels.
- Haplotype generation now recognises regions which are likely to contain 'interacting' variation - basically non-independent indels - and groups them together when possible.
- Some minor efficiency improvements to the trio model should see it run slightly faster.
- Regions which contain massive amounts of variation are now automatically excluded from lagging. This can stop runtimes exploding in very difficult regions.
Bug fixes
- Resolves a bug which could cause VCF records to contain a single alt '*' allele.
- Closed an infinite loop in the assembler.
- Fixes a bug in VCF reading which could drop a record.
Other changes
- There is now a
--very-fastoption in addition to--fast. - The default read memory footprint has been increased to 6GB.