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0.1.13-alpha

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@dancooke dancooke released this 11 Apr 10:51
· 3017 commits to master since this release

This release contains bug fixes and minor performance improvements, it also switches on the assembler by default.

Bug fixes

  • Fixes a bug which could cause very large regions to be considered, resulting in memory overflow due to too many reads being read.
  • A bug causing incorrect de novo haplotype priors due to overflow in the simd alignment routine has been resolved by capping the de novo mutation probability.
  • Fixes a few suitable bugs in haplotype generation.

Improvements

  • The assembler now removes more false positive bubbles due to cycles.
  • De novo mutations which cause reversion to the reference are flagged as REVERSION in the INFO field.
  • Candidates from raw cigar alignments are now filtered depending on a calculated probability or read misalignment.

Other changes

  • The assembler is now on be default.
  • The penalty for matching to an 'N' has been set to 2.
  • More informative debug logging.
  • Unmapped reference contigs can now be ignored with the --ignore-unmapped-contigs option.