0.1.5-alpha
Pre-release
Pre-release
·
3698 commits
to master
since this release
This release contains numerous bug fixes and enhancements:
Bug fixes
- Fixes bug in assembler which could cause segmentation faults.
- Fixes bug in haplotype generation which could cause exceptions.
- Fixes bad VCF genotype output for somatic variants (e.g. 2|0).
- Prevents spurious "Not a BGZF file" warning.
- Building fixes.
Key improvements
- Many improvements have been made to the cancer calling model. In particular specificity has been significantly improved. A model posterior is now reported by default which can be used to hard filter calls. Runtime has been improved, but still needs much work.
- The assembler can now selectively extracts bubbles of a minimum weight, increasing both specificity and sensitivity.
Other changes
- Command line options have been added for the new features.
- The command line options
--debugand--tracecan now take arguments (file paths) to write the respective logs to. - Downsampling limits have been increased.
- Some other command line option names and default values have changed.