rnadraw

RNA secondary structure SVG renderer. Takes dot-bracket notation and produces publication-quality SVG graphics.

Features

• Dot-bracket and dot-bracket-plus (+ strand breaks) notation
• Nucleotide coloring (A/U/G/C) and equilibrium probability gradient
• Automatic stem alignment
• 3' direction arrows
• Available as CLI, Rust library, and WASM module

Usage

CLI

# Nucleotide coloring
rnadraw -s "(((...)))" -q GGGAAACCC -c

# Probability coloring
rnadraw -s "(((...)))" -q GGGAAACCC -p 0.9,0.8,0.7,0.5,0.3,0.5,0.7,0.8,0.9

# JSON coordinate output
rnadraw -s "(((...)))" -f json

# Multi-strand (dot-bracket-plus)
rnadraw -s "((.+.))" -q GGAACCC -c

WASM

import init, { draw_svg_with_options } from './rnadraw_wasm.js';

await init();

const svg = draw_svg_with_options(
  '(((...)))',
  'GGGAAACCC',
  JSON.stringify({ probabilities: [0.9, 0.8, 0.7, 0.5, 0.3, 0.5, 0.7, 0.8, 0.9] })
);

Rust

use rnadraw_core::svg::SvgOptions;

let svg = rnadraw_core::draw_svg("(((...)))", Some("GGGAAACCC"), &SvgOptions::default());

Build

Requires Nix with flakes enabled.

nix build          # CLI binary
nix build .#wasm   # WASM package (wasm-bindgen)
nix build .#wasi   # WASI binary

Acknowledgments

The layout algorithm was developed by studying the visualization output of the NUPACK web application. This project contains no NUPACK source code and is not affiliated with or endorsed by Caltech or the NUPACK team.

License

MIT