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Enable fastq outputs#146

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matthdsm merged 11 commits intodevfrom
feat/fastq_output
Dec 5, 2025
Merged

Enable fastq outputs#146
matthdsm merged 11 commits intodevfrom
feat/fastq_output

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@matthdsm matthdsm commented Dec 4, 2025

  • Add new aligner option false to disable alignment for a sample
  • Drop support for unaligned cram files
  • Add fastq output for unaligned samples

This PR enables us to deprecate the stand-alone demultiplexing script

closes #101

PR checklist

  • This comment contains a description of changes (with reason).
  • If you've fixed a bug or added code that should be tested, add tests!
  • If you've added a new tool - have you followed the pipeline conventions in the contribution docs
  • Make sure your code lints (nf-core pipelines lint).
  • Ensure the test suite passes (nextflow run . -profile test,docker --outdir <OUTDIR>).
  • Check for unexpected warnings in debug mode (nextflow run . -profile debug,test,docker --outdir <OUTDIR>).
  • Usage Documentation in docs/usage.md is updated.
  • Output Documentation in docs/output.md is updated.
  • CHANGELOG.md is updated.
  • README.md is updated (including new tool citations and authors/contributors).

@matthdsm matthdsm requested a review from nvnieuwk December 4, 2025 20:26
@matthdsm matthdsm linked an issue Dec 4, 2025 that may be closed by this pull request
@matthdsm matthdsm self-assigned this Dec 4, 2025
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LGTM

@matthdsm matthdsm merged commit 5edb0e2 into dev Dec 5, 2025
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@matthdsm matthdsm deleted the feat/fastq_output branch December 5, 2025 13:03
@matthdsm matthdsm mentioned this pull request Dec 9, 2025
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Add fastq output option

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