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@omicverse

omicverse

Building interoperable open-source tools for next-generation omics data analysis.

omicverse

Welcome to omicverse!

omicverse is a community-built open-source ecosystem for omics data analysis in Python — from foundational I/O and reimagined algorithms to end-user interfaces. Everything you see below is open to contribution, whether you bring a new algorithm, a tutorial, or a port of an R package.

Architecture

                                                      omicverse
                                                          │
              ┌─────────────────────────┬─────────────────┴─────────────┬────────────────────────────────┐
            Tools                   Tutorials                      Algorithms                       Foundations
              │                         │                               │                                │
        ┌─────┴─────┐            ┌──────┴──────┐           ┌────────────┼─────────────┐                  │
        │           │            │             │           │            │             │                  │
   omicverse-   omicclaw   single_cell_      your      In-house    Integrated     R bridges         anndata-oom
    notebook                 tutorial      tutorial
                                            welcome                                   │
                                                                               ┌──────┴──────┐
                                                                               │             │
                                                                          py-monocle2   py-CellChat
                                                                                         (planned)

In-house · original ML / DL methods — contributions welcome  |  Integrated · best-in-class methods unified under one API

Here's how to get started:

Pinned Loading

  1. omicverse omicverse Public

    A python library for multi omics included bulk, single cell and spatial RNA-seq analysis.

    Python 951 116

  2. anndata-oom anndata-oom Public

    Out-of-memory AnnData powered by Rust — a drop-in replacement for anndata.AnnData that keeps the expression matrix on disk and runs entire preprocessing pipelines

    Jupyter Notebook 1

  3. omicclaw omicclaw Public

    omicverse agent skill

    JavaScript 27 4

  4. omicverse-notebook omicverse-notebook Public

    JupyterLab plugin that brings the omicverse-web DataFrame and AnnData preview ideas into a standalone package.

    CSS 1

Repositories

Showing 10 of 12 repositories
  • omicverse Public

    A python library for multi omics included bulk, single cell and spatial RNA-seq analysis.

    omicverse/omicverse’s past year of commit activity
    Python 951 GPL-3.0 116 17 0 Updated Apr 19, 2026
  • py-dada2 Public

    A pure-Python re-implementation of DADA2 (Callahan et al., Nature Methods 2016) for exact amplicon sequence variant (ASV) inference from amplicon sequencing data.

    omicverse/py-dada2’s past year of commit activity
    Python 0 GPL-3.0 0 0 0 Updated Apr 19, 2026
  • py-scDblFinder Public

    Pure-Python port of R scDblFinder for fast doublet detection in scRNA-seq

    omicverse/py-scDblFinder’s past year of commit activity
    Python 0 0 0 0 Updated Apr 18, 2026
  • py-DoubletFinder Public

    A pure-Python re-implementation of DoubletFinder (McGinnis et al., Cell Systems 2019) for computational doublet detection in single-cell RNA-seq data.

    omicverse/py-DoubletFinder’s past year of commit activity
    Python 0 0 0 0 Updated Apr 18, 2026
  • py-mclustR Public

    A pure-Python re-implementation of CRAN mclust (Scrucca, Fop, Murphy, Raftery 2016) — Gaussian mixture model clustering with all 14 covariance parameterizations and BIC-driven model selection.

    omicverse/py-mclustR’s past year of commit activity
    Python 0 GPL-3.0 0 0 0 Updated Apr 18, 2026
  • py-miloR Public

    A pure-Python re-implementation of Milo (Dann et al., Nature Biotech. 2022) for single-cell differential abundance testing on k-nearest-neighbour neighbourhoods.

    omicverse/py-miloR’s past year of commit activity
    Python 0 GPL-3.0 0 0 0 Updated Apr 18, 2026
  • .github Public
    omicverse/.github’s past year of commit activity
    0 0 0 0 Updated Apr 18, 2026
  • py-monocle2 Public

    A pure-Python re-implementation of Monocle 2 (Qiu et al., Nature Methods 2017) for single-cell trajectory inference.

    omicverse/py-monocle2’s past year of commit activity
    Python 0 GPL-3.0 0 0 0 Updated Apr 18, 2026
  • anndata-oom Public

    Out-of-memory AnnData powered by Rust — a drop-in replacement for anndata.AnnData that keeps the expression matrix on disk and runs entire preprocessing pipelines

    omicverse/anndata-oom’s past year of commit activity
    Jupyter Notebook 1 0 0 0 Updated Apr 17, 2026
  • omicverse-notebook Public

    JupyterLab plugin that brings the omicverse-web DataFrame and AnnData preview ideas into a standalone package.

    omicverse/omicverse-notebook’s past year of commit activity
    CSS 1 0 0 0 Updated Mar 30, 2026

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