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plantgraph-database

Claude Code skill for PlantGraph — Neo4j knowledge graph + REST API for plant gene annotations, interactions, co-expression, orthologues, GO terms, pathways, protein structures, and enrichment.

14.5M+ nodes, 47.9M+ relationships, 127 species, 132 node types, 149 relationship types. 140+ data sources, 42 real-time enrichment services. Built at UPSC (Umeå Plant Science Centre).

Graph contents

  • Gene annotations (GO, PO, protein domains, MapMan bins, pathways)
  • Protein-protein interactions, co-expression networks
  • Cross-species orthologues and paralogues
  • TF binding (DAP-seq validated)
  • GWAS trait associations
  • Histone marks, epigenetic data
  • Single-cell expression profiles
  • Nutrient/pathogen response data
  • 290K+ publications

Species

Arabidopsis thaliana, Brassica napus, Triticum aestivum, Oryza sativa (japonica + indica), Brachypodium distachyon, Zea mays, Populus trichocarpa, and 120+ more.

Not in graph: Hordeum vulgare, Brachypodium sylvaticum — orthologue chain strategies documented.

Install

mkdir -p ~/.claude/skills/plantgraph-database
cp SKILL.md ~/.claude/skills/plantgraph-database/SKILL.md

What the skill covers

Invoke /plantgraph-database in Claude Code. Provides:

  • JWT auth setup and rate limits
  • REST API reference: Graph, Enrichment, AI, Paper Evidence endpoints
  • 42 enrichment sources (UniProt, STRING, AlphaFold, KEGG, InterPro, Expression Atlas, ...)
  • AI: question generation, hypothesis generation, GNN predictions, chat
  • Paper evidence: abstract/PDF scoring, claim verification (SSE)
  • ID format rules per species (Arabidopsis l.name, others l.id)
  • Phytozome-to-PlantGraph ID conversion
  • Cypher query patterns for common tasks
  • Full schema: 132 node labels, 149 relationship types with counts
  • R and Python integration with auth

License

MIT

About

Claude Code skill for querying PlantGraph Neo4j knowledge graph (plantgraph.se) - 1.6M plant loci, 60+ species

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