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#PyGProfile

Installation

Clone this repository and then:

$ cd PyGProfile/
$ python setup.py install --user

This will install the scripts in the pygprofile/scripts directory. For more information on the individual scripts, use the --help command after each script.

##Summary

  • pygp_go.py - TopGO, GOstats and goProfiles wrapper for running GO enrichment analysis from DESEQ2 results or custom input. Also a GO term finder included
  • pygp_path.py - Wrapper for SPIA pathway enrichment analysis and also a simple hypergeometric test for pathway gene enrichment.
  • pygp_pheno.py - Takes an expression matrix with ensembl gene ids on the first column and returns a matrix containing phenotypic annotations from MGI
  • pygp_tfs.py - Selects mouse TF's from a gene expression matrix. Uses AnimalTFDB for annotation of TF's

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PyGProfile is a Python module to profile gene lists using Gene Ontology, Pathways and phenotypic annotation

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