The Adobe font obfuscation algorithm key is built using the publication identifier.
If it is empty, or just urn:uuid:, the deobfuscation will crash with a "Division by zero" error because the key is empty:
https://github.com/readium/r2-streamer-swift/blob/4067b31f7e88306d66bcef253b5fb538b7b0be68/r2-streamer-swift/Parser/EPUB/Resource%20Transformers/EPUBDeobfuscator.swift#L69
If the key is empty, the deobfuscator should just return the data with transformation.
I have an EPUB to test the issue that I can send privately but not share here.