I am a student researcher at IISER TVM using scRNA-seq to study regulatory rewiring in P. vivax liver-stage transitions (hypnozoite to schizont). I plan to apply BoostDiff by treating my thousands of cells as individual "samples".
Could you clarify if the DVI criterion is robust against the high sparsity and dropout rates typical of single-cell data?
I am a student researcher at IISER TVM using scRNA-seq to study regulatory rewiring in P. vivax liver-stage transitions (hypnozoite to schizont). I plan to apply BoostDiff by treating my thousands of cells as individual "samples".
Could you clarify if the DVI criterion is robust against the high sparsity and dropout rates typical of single-cell data?