Releases: sgalg/Genomica
Releases · sgalg/Genomica
Genomica v2.0.1
The version 2.0.1 of Genomica has been released
Major updates:
- Genomica now includes a comprehensive data frame pre-check, allowing users to easily identify potential discrepancies in the input data frames before running analyses.
- Linear mixed model diagnosis. A new output directory, Model_Diagnosis, provides a comprehensive analysis of the model residuals, testing for normality, heteroscedasticity and outliers.
- Users can now specify the significance threshold below which adjusted p-values are considered significant.
- Users can now specify the resolution of the figures.
- The argument "Already_Log10_transformed = c('NO')" is deprecated. The new argument name is "Log10_Transf" (Default = TRUE). If Log10_Transf=FALSE, the log10 (n+1) transformation of the features in the object Data will not be performed.
Genomica v1.2.0
Genomica provides a suite for the analysis of functional orthologs from the KEGG Orthology (KO) database. Genomica is based on a linear mixed model approach, whilst also allowing to test for interactions between maximum two predictors, therefore outputting both a list of significant, FDR adjusted KOs across the treatment layout and the results of the enrichment analysis based on the LMM-informed enriched or depleted orthologs, both in the different treatment groups and cumulatively.