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dotfiles

macOS dev environment for bioinformatics on Apple Silicon — zsh, Homebrew, Claude Code, modern CLI tools.

What's included

Directory Contents
shell/ zshrc (GNU tools, fzf, history, completion, aliases), zprofile
git/ gitconfig (rebase, rerere, histogram diff), global gitignore
ssh/ SSH config (ControlMaster multiplexing, keychain, GitHub)
claude/ CLAUDE.md, settings.json (hooks, plugins), custom commands
macos/ defaults.sh — 50+ macOS developer productivity settings
Brewfile Declarative Homebrew packages (CLI, dev tools, bioinformatics)

Quick start

git clone https://github.com/shandley/dotfiles.git ~/Code/tools/dotfiles
cd ~/Code/tools/dotfiles
chmod +x install.sh
./install.sh

The installer runs interactively by default, prompting for each section.

Selective install

./install.sh --link   # symlink dotfiles only
./install.sh --brew   # install Homebrew packages only
./install.sh --macos  # apply macOS defaults only
./install.sh --all    # everything

Prerequisites

  • Apple Silicon Mac (M1/M2/M3/M4)
  • Xcode Command Line Tools (xcode-select --install)

Key decisions

  • GNU over BSD: GNU coreutils, findutils, sed, tar, grep, and gawk replace BSD defaults on PATH for Linux compatibility
  • Symlinks, not copies: install.sh symlinks files from this repo into $HOME, so edits in either location stay in sync
  • No secrets: No tokens, keys, or credentials are stored in this repo
  • Rebase workflow: Git is configured to rebase on pull, with rerere enabled for conflict memory
  • Modern CLI: fd (find), bat (cat), eza (ls), fzf (fuzzy finder), ripgrep (grep) are installed and aliased

Customization

  • Brewfile: Add/remove packages, then run brew bundle --file=Brewfile
  • macOS defaults: Review macos/defaults.sh and comment out settings you don't want before running
  • Git identity: git/gitconfig contains name and email — update for your own use
  • SSH keys: Update ssh/config with your own IdentityFile path

Credits

Inspired by mathiasbynens/dotfiles and holman/dotfiles.

License

MIT

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macOS dotfiles for bioinformatics on Apple Silicon — zsh, Homebrew, Claude Code, modern CLI tools

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