Question about logarithmization in scvelo.pp.filter_and_normalize #1199
Unanswered
elifdogandar
asked this question in
Q&A
Replies: 0 comments
Sign up for free
to join this conversation on GitHub.
Already have an account?
Sign in to comment
Uh oh!
There was an error while loading. Please reload this page.
Uh oh!
There was an error while loading. Please reload this page.
-
Hi, I have a question/request:
I have data coming from another analysis merged with loom data with spliced/ unspliced counts. After merging adata with loom file, and apply scvelo.pp.filter_and_normalize, it notices that adata X was preprocessed and doesn't normalize it but logarithmizes anyways. It causes X to be logarithmized twice, once in the earlier analysis and once with scvelo. Is it possible to apply
layers_log={'X', 'spliced', 'unspliced'}similar to what was discussed here: question about normalization. In a way that I will be allowed to decide which layers to be logarithmized?Or, alternatively, would it be okay to do that: Applying
filter_and_normalizeonly to loom file and merge afterwards such as:Thank you very much for the scVelo :)
Edit: After some search, I fell like logarithm is already only applied to X to begin with. Is it true? Then when I set log to False, problem will be solved.
Beta Was this translation helpful? Give feedback.
All reactions