Skip to content
Merged
Show file tree
Hide file tree
Changes from all commits
Commits
File filter

Filter by extension

Filter by extension


Conversations
Failed to load comments.
Loading
Jump to
Jump to file
Failed to load files.
Loading
Diff view
Diff view
2 changes: 1 addition & 1 deletion .github/workflows/test.yml
Original file line number Diff line number Diff line change
Expand Up @@ -22,5 +22,5 @@ jobs:
run: |
python -m pip install --upgrade pip setuptools
pip install poetry
poetry install
poetry install --no-root
- run: poetry run mkdocs build
57 changes: 57 additions & 0 deletions src/archive/2025/2025-01-16.md
Original file line number Diff line number Diff line change
@@ -0,0 +1,57 @@
# Jan - Graeme Koelwyn

!!! info "Event Details"

**Date/Time:**

Thursday, January 16th, 2025 :material-clock: 11:00am - 12:30pm PT

**Location:**

:material-video: Remote

/// html | div[class="bio"]

![headshot](./images/graeme-koelwyn.png)

/// html | div

**Featured Speaker**: Dr. Graeme Koelwyn

**Talk Title:** Inflammatory memory: using ‘omics tools to illuminate new pathobiology in heart disease

<!-- ![type:video](https://www.youtube.com/embed/<CODE>) -->

**Affiliation:**

- SFU, Assistant Professor with the Department of Health Sciences, Canada Research Chair Tier II in Public Health 'Omics in Exercise and Disease

///

///

**Bio:**

Dr. Graeme Koelwyn is the Dr. James Hogg Chair in Public Health ‘Omics in Exercise and Disease at St Paul’s Hospital and an Assistant Professor in the Faculty of Health Sciences at Simon Fraser University in Vancouver, Canada. He received his PhD in Pathobiology and Translational Medicine at the NYU Grossman School of Medicine in 2019. He then completed his postdoctoral training at Memorial Sloan Kettering Cancer Center in New York City. He joined SFU and HLI in 2021. The overarching goal of the Koelwyn lab is to apply a translational, ‘omics-based approach for understanding how heart, lung and/or oncologic diseases communicate with each other through immune-specific mechanisms, leading to adverse systemic, tissue, and cellular responses. It also seeks to demonstrate how exercise – a low-cost public health strategy – can therapeutically improve immune function to protect from these diseases and their deleterious interactions.

**Abstract:**

A heart attack, or myocardial infarction, remains a leading cause of morbidity and mortality in Canada, with over 60,000 Canadians entering emergency rooms annually. The recovery from a heart attack requires a swift and coordinated response from our innate immune system, which responds to inflammatory signals generated by the infarct. Historically, it was believed this immune response, coordinated by monocytes and macrophages to clear debris and heal damaged tissue, had no lasting effect on the immune system. However, recent evidence from our group and others have shown this is not the case. In this talk, I’ll discuss the recently developed concept of inflammatory memory, wherein monocytes and macrophages acquire ‘learned’ behavior following inflammatory events such as a heart attack, via epigenetic modifications, which result in long-term altered responses to subsequent immune challenges. I’ll also discuss the ‘omics tools used to identify heart attack-induced inflammatory memory, and the effect of such memory on future disease risk.

---

/// html | div[class="bio"]

![headshot](./images/rituparna-banerjee.jpeg)

/// html | div

**Trainee Speaker:** Rituparna Banerjee

**Affiliation:** PhD candidate in bioinformatics program jointly supervised by Daniel Coombs and Matthew Pennell

**Talk Title**: Exploring B cell repertoire evolution post-vaccination using mathematical modelling and phylogenetic trees

///

///
Binary file added src/archive/2025/images/graeme-koelwyn.png
Loading
Sorry, something went wrong. Reload?
Sorry, we cannot display this file.
Sorry, this file is invalid so it cannot be displayed.
Loading
Sorry, something went wrong. Reload?
Sorry, we cannot display this file.
Sorry, this file is invalid so it cannot be displayed.
4 changes: 2 additions & 2 deletions src/index.md
Original file line number Diff line number Diff line change
Expand Up @@ -11,6 +11,6 @@ Visit our sister groups for bioinformatics events in Montreal ([MonBUG](https://
## VanBUG Monthly Event

{%
include-markdown "./archive/2024/2024-11-21.md"
start="# Nov - Can Alkan"
include-markdown "./archive/2025/2025-01-16.md"
start="# Jan - Graeme Koelwyn"
%}
18 changes: 9 additions & 9 deletions src/schedule.md
Original file line number Diff line number Diff line change
Expand Up @@ -18,7 +18,7 @@

- ### Nov 21st, 2024, Thursday

:material-clock: 11:00am - 1:30pm PT
:material-clock: 11:00am - 12:30pm PT

:material-map-marker: Remote

Expand All @@ -34,21 +34,21 @@

/// html | div[class="timeline"]

- ### Jan 16th, 2024, Thursday
- ### Jan 16th, 2025, Thursday

:material-clock: 11:00am - 1:30pm PT
:material-clock: 11:00am - 12:30pm PT

:material-map-marker: Remote

:material-video: Connection Details TBA

Featured Speaker: TBA
Featured Speaker: Dr. Graeme Koelwyn

Trainee Speaker: TBA
Trainee Speaker: Rituparna Banerjee

- ### Feb 20th, 2024, Thursday
- ### Feb 20th, 2025, Thursday

:material-clock: 11:00am - 1:30pm PT
:material-clock: 11:00am - 12:30pm PT

:material-map-marker: Remote

Expand All @@ -58,9 +58,9 @@

Trainee Speaker: TBA

- ### March 20th, 2024, Thursday
- ### March 20th, 2025, Thursday

:material-clock: 11:00am - 1:30pm PT
:material-clock: 11:00am - 12:30pm PT

:material-map-marker: Remote

Expand Down