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@spond spond released this 27 Feb 22:06
2.5.96
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Learn about vigilant mode.

HyPhy Release Notes: Version 2.5.96

Overview

This release introduces B-STILL (Beta-STILL), a specialized selection analysis framework designed to identify site-level evolutionary stasis (invariance) using a Bayesian FUBAR-style approach.

New Features

  • B-STILL (Selection Analysis): A new method for detecting sites that exhibit significantly less variation than expected under neutral models.

    • Implemented in res/TemplateBatchFiles/SelectionAnalyses/B-STILL.bf.
    • Optimized for large-scale genomic datasets to identify highly conserved functional motifs.
    • Added to files.lst for keyword-based invocation via the command line.

  • Version Update: Updated internal version string to 2.5.96.

For more information on running B-STILL, use:
hyphy b-still --alignment <path> --tree <path>

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