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v0.2.0

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@Bribak Bribak released this 16 May 07:06
· 19 commits to main since this release
  • both synthetic and templated modes will no longer use Dirichlet distributions but rather Gaussian copulas, informed by Ledoit-Wolf-shrunk covariances and empirical marginals estimated from class-pooled data from glycowork (synthetic) or specific datasets (templated)
  • missing data simulation has been switched from a power function to a logistic function
  • batch effect simulation can now also simulate multiplicative batch effect (in addition to additive batch effects)
  • simulate_paired workflow has been added to simulate same-sample multi-glycomics data with tunable coupling strength (e.g., N- and O-glycomics data of the same samples)