v1.0.0 - Stable Release 🎉

🎉 PrimerLab v1.0.0 - Stable Release

First production-ready release of PrimerLab!

Highlights

• ✅ 1286+ passing tests with comprehensive coverage
• ✅ Full PCR Workflows: Standard PCR, qPCR, Nested PCR, Semi-Nested PCR
• ✅ Complete Analysis Suite: BLAST off-target, In-silico PCR, Dimer matrix
• ✅ Multiple Installation Options: Docker, Conda, Pip
• ✅ Comprehensive Documentation: API reference, CLI guide, tutorials

Installation

PyPI (Recommended)

pip install primerlab-genomic

Docker

docker pull ghcr.io/engkinandatama/primerlab-genomic:1.0.0
docker run ghcr.io/engkinandatama/primerlab-genomic:1.0.0 --version

Conda

git clone https://github.com/engkinandatama/primerlab-genomic.git
cd primerlab-genomic
conda env create -f environment.yml
conda activate primerlab
pip install -e .

Quick Start

# PCR primer design
primerlab run pcr --config your_config.yaml

# qPCR with TaqMan probe
primerlab run qpcr --config qpcr_config.yaml

# Nested PCR
primerlab run nested --config nested_config.yaml

What's New in v1.0.0

Added

• Production Status: Changed from Beta to Production/Stable
• Report Standardization: Unified report format across all workflows
• Documentation: Complete tutorials, API reference, configuration guide
• Docker Support: Multi-stage build with ViennaRNA and BLAST+ included
• PyPI Publishing: Automated release via GitHub Actions

Changed

• Version bump from 0.9.x to 1.0.0
• Updated all badges and documentation to reflect stable release

Documentation

• 📚 Full Documentation
• 🚀 Getting Started
• 📖 CLI Reference
• 🔧 API Reference
• 📝 Tutorials

Requirements

• Python 3.10+
• primer3-py >= 2.0.0
• biopython >= 1.80
• Optional: ViennaRNA, BLAST+ (included in Docker)

Full Changelog

See CHANGELOG.md