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xvcfview

This workflow provides the full power of bcftools view to subset, subsample, and filter VCF files.

input

All input files are referenced with either gs:// or drs:// URIs.

parameter required default description
input_vcf required Input VCF file.
input_vcf_index optional VCF index file. If omitted, an index is created during execution. Instructions for creating index files are here.
samples optional File of samples to be included in the output VCF. There should one sample per line. Additional information is here.
regions optional File of regions to be included in the output VCF. The file should contain tab separated columns of chromosome (e.g. 'chr15'), start position, and optionally end position. Additional information is here.
view_options optional -Oz Additional parameters to pass to the bcftools view command. If modified, view_options should typically include -Oz to produce a gzipped output VCF.
filters optional Filter arguments to pass into bcftools view. Filters will be applied in a separate, subsequent, call to bcftools view.
output_filename optional output.vcf.gz Name of the output vcf file.
cpu optional 8 Number of CPU cores.
memory optional 64 Amount of RAM in GB
preemptible optional 0 Whether to use preemptible instances, which are cheaper but my be revoked during execution.

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A WDL workflow to subset, subsample, and filter VCF files using bcftools.

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