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PowerTOST v1.4-5

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@Detlew Detlew released this 19 May 18:19
v1.4-5
312a4a0
  • Man pages for non-inferiority functions updated to include a description of the underlying hypotheses
  • Remaining man pages updated where term 'Null (true) ratio' was mentioned instead of 'True ratio'
  • Two new test scrips in /test subdirectory added: test_ABEL.R and test_RSABE which recalculate the sample size tables given in Thotfalusi & Endrenyi "Sample Sizes for Designing Bioequivalence Studies for Highly Variable Drugs". Contributed by Helmut.
  • power.scABEL.sdsims() now has an argument design_dta to specify the design via a data.frame. May be useful for considering missing data. Attention! This feature is experimental because the data.frame is not checked at moment.
  • Bug in power.scABEL.sdsims() fixed which gave power=NA if alpha=0.
  • Internal change of coding in design helpers (repeated creation of data.frame with design characteristics avoided).
  • Typo corrected in Expected_Power_for_TOST.pdf.
  • Updated functions scABEL.ad() and sampleN.scABEL.ad() to allow subject data simulations via power.scABEL.sdsims() if regulator = "EMA". Removed regulator = "ANVISA".
    Changed the order of sequences to be consistent with the other functions of PowerTOST.
  • Renamed the variable 'adj. alpha' in sampleN.scABEL.ad() to 'alpha.adj' for consistency with scABEL.ad(). Bug corrected if pre-specified alpha gives TIE <0.05.
  • Removed regulator = "ANVISA" from pa.scABE().
  • Small bug in the S3 method plot for class 'pwrA' corrected (text in the 4th box was truncated on top if saved as a PDF). Replaced text() by TeachingDemos::shadowtext() to enhance legibility (interfered with underlying grid).
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