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EmadHassanin/README.md

Emadeldin Hassanin

Senior Data Scientist | Statistical Genetics | Machine Learning


Overview

Senior Data Scientist with 7+ years of experience designing, validating, and deploying data-driven models across biomedical and population-scale datasets. Strong background in statistics, applied machine learning, and Bioinformatics with experience spanning research, production pipelines, and stakeholder-facing analytics.


Technical Leadership

  • Design end-to-end analytical pipelines (QC → modeling → validation → reporting)
  • Translate complex statistical results into actionable insights
  • Ensure reproducibility, scalability, and robustness of analyses
  • Collaborate with cross-functional teams (research, engineering, product)
  • Mentor junior researchers and data scientists

Domain Expertise

  • Polygenic Risk Scores (PRS) & genetic risk prediction
  • GWAS, WES/WGS, large-scale genomic data
  • Epidemiology & biostatistics
  • Multi-omics integration
  • Predictive modeling for complex diseases

Core Technologies

Languages

  • R, Python, SQL, Bash

Machine Learning & Statistics

  • Regularized regression (Lasso, Ridge, Elastic Net)
  • Tree-based models (XGBoost, LightGBM)
  • Model evaluation & calibration
  • Feature engineering for structured data

Genomics & Bioinformatics

  • PLINK, Hail, GWAS workflows
  • WES / WGS analysis
  • Pathway & gene-set enrichment

Data & Infrastructure

  • Linux, HPC (SLURM)
  • Cloud: AWS, GCP
  • Version control: Git
  • BI & Visualization: Power BI, Tableau, ggplot2, Matplotlib, Plotly

📌 Selected Projects

  • Pathway-specific PRS in Epilepsy
    Developed and validated pathway-level PRS models across generalized and focal epilepsy cohorts.

  • Scalable GWAS & PRS Pipelines
    Built reproducible pipelines handling large-scale genomic datasets with rigorous QC and validation.

  • Risk Prediction & Analytics Dashboards
    Designed dashboards to communicate complex genetic risk results to non-technical stakeholders.


📊 Research & Impact

  • Contributions to international consortia (ILAE, Epi25)
  • Reviewer for peer-reviewed genetics and epidemiology journals
  • Focus on translating genetic insights into interpretable risk models

📫 Contact

Popular repositories Loading

  1. combining_prs_gps combining_prs_gps Public

    Combining polygenic risk scores with gene-based scores

    HTML 2

  2. hpo_sim_gene hpo_sim_gene Public

    Forked from galerp/hpo_sim_gene

    This is a repository for work within the Helbig Lab research team and outside collaborators.

    R

  3. iosp iosp Public

    Forked from koncina/iosp

    IOSlides Plus

    R

  4. Multi_drug_trials Multi_drug_trials Public

    TeX

  5. genomic_compression_encryption_benchmarking genomic_compression_encryption_benchmarking Public

    Python

  6. poster_prs_gps poster_prs_gps Public

    Poster AGD ("Combining polygenic risk scores with gene-based burden scores")

    HTML