release/98.0

New data

• Human GRCh38 cache files now contain variants from dbSNP152
• MANE attributes are now included within VEP cache files

New and updated VEP options

• --clin_sig_allele has been updated to be used by default
• --custom_multi_allelic prevents VEP from assuming that comma separated lists in custom annotations are allele specific

VEP installer

• HTSLib v1.9 is now installed by default (previously v1.3.2)
• Bio::DB::HTS v2.11 is now installed by default (previously v2.9)
• New option 'PLUGINSDIR' allows you to specify the installation directory for plugins

New VEP plugin

• satMutMPRA measures variant effects on gene RNA expression for 21 regulatory elements