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EvgenyZhvansky edited this page Aug 28, 2021 · 3 revisions

Mass spectrometry imaging is a promising tool complement to the histology study for evaluation of presence of different tissue types in the sample. To make this method faster, more accurate and precise we have presented earlier the cosine similarity measure maps (CSMM). The method provides the spatial distribution of cosine similarity measure metrics between chosen MSI pixel and the rest of the image. In cases when samples under test are heterogeneous and not guaranteed to have clear clusters with distinct borders, it is interesting to analyze the heterogeneity, area borders and their sensitivity to reference CSSM pixel selection. Here we present the software for interactive building of CSMM for different parameters, their visual analysis and saving such CSMM in publication-ready quality without additional programming.

Manual is available here

The screencast of the SSM display tool is available here:

Interactive_CSSM screencast

Examples of the data are here

Cases of analyses are available here

The last release is available here

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