Recover and validate the bioHSI Figure 4g manual ROI coordinates

[JVLegend]

Blocker

T8c is paused because the official Figure 4 notebook loads manually_defined_rectangle_coordinates.json, but that artifact is absent from the public Zenodo archive, repository, release assets, branches, and Git history.

Author request: itai-levin/bioHSI#2
Reproduction diagnosis: https://github.com/JVLegend/HyperMix/blob/main/results/real_target_reproduction_diagnosis.md

Frozen evidence

The candidate geometry failed the preregistered gate:

• HyperMix port: MAE 0.156114, Pearson r 0.375901
• direct tagged source: MAE 0.158137, Pearson r 0.145083
• gate: MAE <= 0.01 and Pearson r >= 0.99

No detector comparison has been performed.

Acceptable independent bridge

Any one of:

• exact manual rectangle JSON used for Figure 4g;
• official output directory or score map with those rectangles;
• full-scene coordinates and concentration order;
• deterministic transform linking archived local ROIs to notebook rectangles.

Acceptance

• checksum and cite the recovered public artifact;
• rerun the frozen reproduction gate without moving regions by detector score;
• publish the result whether the gate passes or fails;
• only then decide whether the detector comparison can proceed.

Do not optimize or visually reposition regions from detector outputs.