v2.0.0 - Enhanced GUI with Automated Exon Sequence Retrieval & Cross-Platform Support
🎉 MAGIC GUI — Version 2.0.0
This is the updated release of the MAGIC application, built with Python and Tkinter, now available for Windows, macOS, and Linux.
🔧 What's included:
A standalone executable for Windows, macOS, and Linux — no Python installation required
A revised graphical user interface (GUI) with enhanced usability and error handling
Direct integration with the Ensembl database for automatic exon sequence retrieval
✨ Core features:
🧬 Creation of artificial genome FASTA and GTF files, representative of the minigene splicing assay used for massively parallel sequencing
🔄 Automatic exon sequence retrieval from Ensembl using gene symbol and transcript ID (NM_ or ENST format), supporting GRCh37 and GRCh38 human genome versions
✏️ All fields remain editable for manual adjustments
📂 Final file generation now confirms success and opens the output folder automatically
🚀 How to use:
Download the appropriate executable for your operating system below
Double-click to run — no installation needed
If Windows SmartScreen warns you, click "More info" → "Run anyway"