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v2.0.0 - Enhanced GUI with Automated Exon Sequence Retrieval & Cross-Platform Support

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@AUCAM AUCAM released this 07 Aug 09:08
· 4 commits to main since this release

🎉 MAGIC GUI — Version 2.0.0
This is the updated release of the MAGIC application, built with Python and Tkinter, now available for Windows, macOS, and Linux.

🔧 What's included:

A standalone executable for Windows, macOS, and Linux — no Python installation required

A revised graphical user interface (GUI) with enhanced usability and error handling

Direct integration with the Ensembl database for automatic exon sequence retrieval

✨ Core features:

🧬 Creation of artificial genome FASTA and GTF files, representative of the minigene splicing assay used for massively parallel sequencing

⚠️ Step-by-step validation and warning system to guide users and prevent input errors

🔄 Automatic exon sequence retrieval from Ensembl using gene symbol and transcript ID (NM_ or ENST format), supporting GRCh37 and GRCh38 human genome versions

✏️ All fields remain editable for manual adjustments

📂 Final file generation now confirms success and opens the output folder automatically

🚀 How to use:

Download the appropriate executable for your operating system below

Double-click to run — no installation needed

If Windows SmartScreen warns you, click "More info" → "Run anyway"