TRGT v5.1.0

Summary of changes:

• Important changes:
  • Added the --fail-reads parameter to trgt genotype. It is now possible to add a fail reads BAM as a separate aligned BAM in addition to the primary --reads BAM. This is useful for PureTarget and other workflows where fail and HiFi reads are aligned separately, since they no longer need to be merged before running TRGT. Adding --fail-reads also disables the default rq filter unless --min-read-quality is set explicitly.
• Added BCF output support to trgt genotype through -O, --output-type (u/b for uncompressed/compressed BCF, v/z for uncompressed/compressed VCF).

Contributors: Tom Mokveld, Guilherme De Sena Brandine, and Egor Dolzhenko

Note: TRGT is still in active development. Please file an issue or reach out by email with questions, bug reports, and feature suggestions.

Linux binary is available below.