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TranscriptoScope Windows v0.4.3

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@Shettima123 Shettima123 released this 12 Jun 07:20
v0.4.3
cc4bdd5

TranscriptoScope Windows v0.4.3

TranscriptoScope is a Windows-friendly local Shiny application for differential gene expression analysis, functional enrichment, and ranked pathway analysis.

Download

Download TranscriptoScope_Windows_v0.4.3.zip from this release, extract it, and run:

Install_TranscriptoScope.bat

After installation, launch TranscriptoScope from the Desktop or Start Menu shortcut.

What This Release Includes

  • Raw read-count analysis with DESeq2.
  • Normalized expression analysis for decimal-valued expression matrices.
  • Fold-change table import modes.
  • PCA, volcano, MA, and regulation-summary plots.
  • ORA enrichment with bundled organism resources.
  • Rosby's Lab-style ORA, defined as protein-coding directional ORA.
  • Ranked pathway analysis with fgsea.
  • Bundled example data, annotation resources, and Windows install scripts.

Changes In v0.4.3

  • Made Windows package installation explicitly non-interactive by forcing binary package installs and suppressing source-package prompts.
  • Added package-install progress messages for cleaner Windows runtime validation.

Validation

The manuscript validation package reports:

  • 71 of 71 core checks passed for TranscriptoScope 0.4.2 statistical workflows.
  • VP-14 Windows deployment validation passed with the repaired 0.4.3 Windows package in a clean Windows 11 standard-user environment and a separate true-offline launch test after dependency setup.

Checksum

SHA256  TranscriptoScope_Windows_v0.4.3.zip  0148DB0BE366AB573BBC13BE038C2545B1F16C7AECCAA4F0F05A69439732F37E

Citation

If you use TranscriptoScope in research, cite this software release and cite the underlying methods/packages used in your analysis, including DESeq2 for differential expression and fgsea for ranked pathway analysis.

Release DOI: 10.5281/zenodo.20659462

Important Notes

This is a research software tool. Users are responsible for reviewing outputs, choosing appropriate statistical settings, and following institutional policies for sensitive or protected datasets.

Microsoft Store Candidate Installer

A Store-style .exe installer is available for Microsoft Partner Center testing and submission preparation:

ext TranscriptoScope_Windows_Store_v0.4.3.exe SHA256 80E49ABAF1590AE3735B62B24BFDA8F5BB5317968CCFD7719EBA3FBC46BE73BA

This installer bundles R 4.6.0 and the required R package library for offline installation. Local host testing passed install, bundled package preflight, local Shiny launch, and uninstall checks. Final Microsoft Store submission should wait for a clean Windows 11 VM install/launch pass and true offline VM pass.

Assets 6
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