TranscriptoScope Windows v0.4.7
TranscriptoScope v0.4.7 expands the validated Network Analysis workflow and its reproducibility exports.
Highlights:
- Added sample-clustering dendrogram output before network interpretation.
- Added scale-free topology fit and mean-connectivity plots plus the underlying candidate-power table.
- Added a gene dendrogram with aligned module-color annotation.
- Added downloadable module-size and module-trait heatmap PNG files.
- Added module enrichment against the current upregulated, downregulated, and combined DEG sets.
- Added six WGCNA CSV tables and five Network Analysis PNG files to the result bundle.
- Extended the exported R rerun script to reproduce scale-free topology and module-enrichment tables.
Validation:
- Core analytical validation passed 71/71 checks and 11/11 protocol items in two fresh R sessions.
- The two core sessions produced identical analytical observations after run metadata was excluded and 12/12 byte-identical saved analytical artifacts.
- VP-16 feature-extension validation passed 14/14 checks.
- Expanded VP-17 WGCNA/Network Analysis validation passed 19/19 checks.
- VP-17 independently verified sample clustering, scale-free topology, gene dendrogram/module colors, module enrichment, all six WGCNA tables, all five network plots, UI/download contracts, result-bundle contents, and reproducibility reruns.
- The end-to-end developer smoke test passed from both the source tree and the packaged ZIP extracted under a path containing spaces.
- Package inspection confirmed version
0.4.7, inclusion of the public VP-17 evidence note, and zero bundled KEGG cache files.
Release notes:
- Built from TranscriptoScope source version
0.4.7. - The Windows ZIP excludes KEGG-derived cache files. KEGG workflows use optional user-initiated KEGG REST access and local user caching.
- The MIT license applies to TranscriptoScope source code and project-authored documentation only; third-party biological resources and R/Bioconductor packages remain subject to their own terms.
- WGCNA outputs are exploratory coexpression results and should not be interpreted as causal regulatory relationships.
Archive:
- Zenodo v0.4.7 DOI: https://doi.org/10.5281/zenodo.21291831
- Stable all-versions Zenodo concept DOI: https://doi.org/10.5281/zenodo.20659461