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TranscriptoScope Windows v0.4.8

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@Shettima123 Shettima123 released this 13 Jul 01:06

TranscriptoScope v0.4.8 improves input handling and refreshes the interface while preserving the validated analytical workflows from v0.4.7.

Highlights:

  • Added automatic input-type detection for raw counts, normalized expression, fold-change plus adjusted-p-value tables, and fold-change-only tables.
  • Kept ambiguous inputs under manual user control and now explains why the app did not change the selected type.
  • Added automatic support for both vertical and horizontal sample-metadata layouts.
  • Added direct XLSX/XLS metadata import from the first worksheet.
  • Added downloadable vertical and horizontal metadata examples.
  • Improved empty states, diagnostic guidance, visual hierarchy, responsive spacing, tabs, forms, buttons, and the application header.

Validation:

  • The full end-to-end developer smoke test passed for raw counts, normalized expression, fold-change modes, ORA, ranked pathway analysis, and WGCNA.
  • Automatic input-type tests passed for all four supported input categories.
  • Vertical and horizontal metadata produced identical aligned metadata for the supplied 12-sample workbooks.
  • Store dependency preflight passed with readxl included.
  • Package inspection confirmed version 0.4.8 and zero bundled KEGG cache files.
  • This release does not change the DESeq2, ORA, fgsea, or WGCNA statistical calculations validated in v0.4.7.

Release notes:

  • Built from TranscriptoScope source version 0.4.8.
  • The Windows ZIP excludes KEGG-derived cache files. KEGG workflows use optional user-initiated KEGG REST access and local user caching.
  • The MIT license applies to TranscriptoScope source code and project-authored documentation only; third-party biological resources and R/Bioconductor packages remain subject to their own terms.
  • Excel support applies to sample metadata. Primary count, expression, and fold-change inputs remain CSV, TSV, or TXT.

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