CRF1A part 3

Variable / Field Name	Section Header	Field Type	Field Label	Choices or Calculations
crf1a3_version		radio	CRF1 Version Completed	1, Unversioned ; 2, 1.0 ; 3, 1.1 ; 4, 1.2 ; 5, 1.3 ; 6, 1.4 ; 7, 1.5 ; 8, 2.0
crf1a_o2_supp	Respiratory Support given at any point during COVID-19 admission	radio	a) Supplemental oxygen	1, Yes ; 0, No ; 2, N/K
crf1a_o2_cpapv		radio	b) Continuous Positive Airway Pressure Ventilation	1, Yes ; 0, No ; 2, N/K
crf1a_o2_blniv		radio	c) Bi-Level Non-Invasive Ventilation	1, Yes ; 0, No ; 2, N/K
crf1a_o2_hfn		radio	d) High Flow Nasal O2	1, Yes ; 0, No ; 2, N/K
crf1a_o2_imv		radio	e) Invasive Mechanical Ventilation	1, Yes ; 0, No ; 2, N/K
crf1a_o2_ecmo		radio	f) Extra-Corporeal Membrane Oxygenation	1, Yes ; 0, No ; 2, N/K
crf1a_treat_at	Were any of the following treatments given during hospitalisation?	radio	a) Antibiotic therapy	1, Yes ; 0, No ; NK, N/K
crf1a_treat_ss		radio	b) Systemic (oral or IV) steroids	1, Yes ; 0, No ; NK, N/K
crf1a_treat_tdac		radio	c) Therapeutic dose anti-coagulation	1, Yes ; 0, No ; NK, N/K
crf1a_treat_proning		radio	d) Proning	1, Yes ; 0, No ; NK, N/K
crf1a_treat_rrt		radio	e) Renal replacement therapy	1, Yes ; 0, No ; NK, N/K
crf1a_treat_tocil		radio	f) Tocilizumab	1, Yes ; 0, No ; NK, N/K
crf1a_treat_saril		radio	g) Sarilumab	1, Yes ; 0, No ; NK, N/K
crf1a_treat_remde		radio	h) Remdesivir	1, Yes ; 0, No ; NK, N/K
crf1a_add_diag_pemt	Were any of these additional diagnoses or complications made during hospitalisation?	radio	a) Pulmonary Embolism/micro thrombi	1, Yes ; 0, No ; NK, N/K
crf1a_add_diag_cvvh		radio	b) Renal failure requiring CVVH or Haemodialysis	1, Yes ; 0, No ; NK, N/K
crf1a_add_diag_myoc		radio	c) Myocarditis	1, Yes ; 0, No ; NK, N/K
crf1a_add_diag_cmp		radio	d) Cardiomyopathy	1, Yes ; 0, No ; NK, N/K
crf1a_add_diag		radio	e) Coronary thrombosis	1, Yes ; 0, No ; NK, N/K
crf1a_studies	Was the patient enrolled in any COVID Studies during hospitalisation?	checkbox	13) Was the patient enrolled in any COVID Studies during hospitalisation?	1, GenOMICC ; 2, RECOVERY ; 22, RECOVERY-RS ; 3, REMAP-CAP ; 4, Synairgen SG016 ; 5, CAN-COVID ; 6, RUXCOVID ; 7, ACCORD-2 ; 8, PACA ; 9, Tocilizumab ; 10, REALIST ; 11, ACTT-EU/UK ; 12, Remdesivir Moderate ; 13, Remdesivir Severe ; 14, COVACTA ; 15, TACTIC-R ; 16, C-19-ACS ; 17, ILIAD-7-UK ; 18, LIBERATE ; 19, ATOMIC2 ; 20, STOP-COVID ; 21, Other
crf1a_genomicc_id		text	GenOMICC ID
crf1a_studies_other		notes	Other COVID IMP studies enrolled
crf1a_egfr_low	Please provide the following values if measured:	radio	14.a) Lowest measured eGFR	1, Enter exact value ; 2, >90 mL/min/1.73m2 ; 3, N/K
crf1a_egfr_low_value		text	14.a) Lowest measured eGFR: Value
crf1a_egfr_low_date		text	14.a) Lowest measured eGFR: Date of sample
crf1a_alt_high		radio	14.b) Highest measured ALT	1, Enter exact value ; NK, N/K
crf1a_alt_high_less_great		dropdown	14.b) Highest measured ALT - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_alt_high_value		text	14.b) Highest measured ALT: Value
crf1a_alt_high_date		text	14.b) Highest measured ALT: Date of sample
crf1a_bnp_done		radio	14.c) BNP Measurements i) Was BNP or NT-proBNP measured during admission?	1, Yes ; 0, No ; NK, N/K
crf1a_bnp_type		radio	14.c) BNP Measurements ii) What measure was used?	1, NT-proBNP ; 2, BNP
crf1a_bnp_unit		radio	14.c) BNP Measurements iii) What units were used?	1, pg/ml ; 2, other
crf1a_bnp_unit_other		text	14.c) BNP Measurements Unit
crf1a_bnp_high_less_great		dropdown	14.c) BNP Measurements iv) Highest level recorded during admission - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_bnp_high		text	14.c) BNP Measurements iv) Highest level recorded during admission: Value
crf1a_bnp_high_date		text	14.c) BNP Measurements iv) Highest level recorded during admission: Date of sample
crf1a_bnp_last		radio	14.c) BNP Measurements v) Level of last measurement prior to discharge	1, Enter exact value ; 2, Same as highest level
crf1a_bnp_last_less_great		dropdown	14.c) BNP Measurements v) Level of last measurement prior to discharge - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_bnp_last_value		text	14.c) BNP Measurements v) Level of last measurement prior to discharge: Value
crf1a_bnp_last_date		text	14.c) BNP Measurements v) Level of last measurement prior to discharge: Date of sample
crf1a_trop_done		radio	14.d) Troponin Measurements i) Was Troponin measured during admission?	1, Yes ; 0, No ; NK, N/K
crf1a_trop_type		radio	14.d) Troponin Measurements ii) What measure of Troponin was used?	1, cTnI ; 2, cTnT ; 3, hs-cTnI ; 4, hs-cTnT
crf1a_trop_unit		radio	14.d) Troponin Measurements iii) What units were used?	1, ng/ml ; 2, other
crf1a_trop_unit_other		text	14.d) Troponin Measurements Unit
crf1a_trop_first_less_great		dropdown	14.d) Troponin Measurements iv) First level recorded during hospital admission - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_trop_first		text	14.d) Troponin Measurements iv) First level recorded during hospital admission
crf1a_trop_first_date		text	14.d) Troponin Measurements iv) First level recorded during hospital admission: Date of sample
crf1a_trop_high		radio	14.d) Troponin Measurements v) Highest level recorded during admission	1, Enter exact value ; 2, Same as first level
crf1a_trop_high_less_great		dropdown	14.d) Troponin Measurements v) Highest level recorded during admission - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_trop_high_value		text	14.d) Troponin Measurements v) Highest level recorded during admission: Value
crf1a_trop_high_date		text	14.d) Troponin Measurements v) Highest level recorded during admission: Date of sample
crf1a_haema_not_done	Haematology results panel (at admission)	checkbox	Please tick any test that is NOT DONE	1, Haemoglobin (Hb) ; 2, White Blood Cell (WBC) count ; 3, Neutrophil count ; 4, Lymphocyte count ; 5, Eosinophil count ; 6, Platelet (PLT) count ; 7, Mean cell volume (MCV) ; 8, INR ; 9, APTT ; 10, D-dimer level ; 11, Fibrinogen level
crf1a_haemo_less_great		dropdown	Haemoglobin (Hb) - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_haemoglobin		text	Haemoglobin (Hb)
crf1a_wbc_less_great		dropdown	White Blood Cell (WBC) Count - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_wbc		text	White Blood Cell (WBC) count
crf1a_neutro_less_great		dropdown	Neutrophil Count - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_neutrophil_count		text	Neutrophil count
crf1a_lympho_less_great		dropdown	Lymphocyte Count - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_haema_lymph		text	Lymphocyte count
crf1a_eos_less_great		dropdown	Eosinophil Count - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_eosinophil_count		text	Eosinophil count
crf1a_plt_less_great		dropdown	Platelet (PLT) Count - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_platelet_plt_count		text	Platelet (PLT) count
crf1a_mcv_less_great		dropdown	Mean Cell Volume (MCV) - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_mcv		text	Mean cell volume (MCV)
crf1a_inr_less_great		dropdown	INR - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_inr		text	INR
crf1a_aptt_less_great		dropdown	APTT - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_aptt		text	APTT
crf1a_d_dimer_less_great		dropdown	D-dimer level - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_d_dimer_unit		radio	D-dimer level - Measurement	1, ug/mL or mg/L ; 2, ng/mL or ug/L
crf1a_d_dimer_assay		radio	D-dimer level - Measurement	1, FEU ; 2, DDU
crf1a_d_dimer_level		text	D-dimer level
crf1a_fib_less_great		dropdown	Fibrinogen level - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_fibrinogen		text	Fibrinogen level
crf1a_biochem_not_done	Biochemistry panel (at admission)	checkbox	Please tick any test that is NOT DONE	1, Sodium (Na) ; 2, Potassium (K) ; 3, Urea ; 4, Creatinine ; 5, eGFR ; 6, Alanine aminotransferase (ALT) ; 7, Alkaline phosphatase (ALP) ; 8, Total Bilirubin ; 9, CRP ; 10, Ferritin ; 11, Magnesium (mg) ; 12, Serum Cortisol ; 13, Procalcitonin ; 14, Interleukin-6
crf1a_na_less_great		dropdown	Sodium (Na) - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_na		text	Sodium (Na)
crf1a_k_less_great		dropdown	Potassium (K) - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_k		text	Potassium (K)
crf1a_urea_less_great		dropdown	Urea - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_urea		text	Urea
crf1a_creat_less_great		dropdown	Creatinine - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_creatinine		text	Creatinine
crf1a_biochem_egfr_90		yesno	Is eGFR value > 90?	1, Yes ; 0, No
crf1a_egfr_int		text	eGFR
crf1a_alt_less_great		dropdown	Alanine aminotransferase (ALT) - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_alt		text	Alanine aminotransferase (ALT)
crf1a_alp_less_great		dropdown	Alkaline phosphatase (ALP) - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_alp		text	Alkaline phosphatase (ALP)
crf1a_bili_less_great		dropdown	Total Bilirubin - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_bilirubin		text	Total Bilirubin
crf1a_crp_less_great		dropdown	CRP - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_crp		text	CRP
crf1a_ferr_less_great		dropdown	Ferritin - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_ferritin		text	Ferritin
crf1a_mg_less_great		dropdown	Magnesium (mg) - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_mg		text	Magnesium (mg)
crf1a_ser_cor_less_great		dropdown	Serum Cortisol - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_serum_cortisol		text	Serum Cortisol
crf1a_procal_less_great		dropdown	Procalcitonin - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_procalcitonin		text	Procalcitonin
crf1a_inter6_less_great		dropdown	Interleukin-6 - Select if test result provided is not an exact value	1, < (Less than) ; 2, > (Greater than)
crf1a_interleukin_6		text	Interleukin-6
crf1a_aki_adm	Acute Kidney Injury Stage	radio	AKI Stage at admission	0, None ; 1, Stage 1 ; 2, Stage 2 ; 3, Stage 3
crf1a_high_aki_adm		radio	Highest AKI Stage during admission	0, None ; 1, Stage 1 ; 2, Stage 2 ; 3, Stage 3
crf1a_isaric_enrol_yn	Co-enrolment in other observational studies	yesno	Has the patient been enrolled in the ISARIC-4C study?	1, Yes ; 0, No
crf1a_isaric_id		text	ISARIC-4C ID