A tunable DNA and protein sequence aligner as a native Windows app, now with on-device AI.
How to run
- Download SequenceAlignerApp-win-x64.zip below.
- Unzip it into a folder.
- Run SequenceAlignerApp.exe.
Self-contained (no .NET install needed). The 3D and AI features use an internet connection for structure data.
New in v1.1
- AI protein analysis: a transformer language model (trained from scratch) scores how related two proteins are, predicts the family of a sequence, and finds similar proteins in a built-in database. Runs on the GPU or NPU (Windows ML).
- AI secondary-structure prediction (helix / sheet / coil), also on the GPU/NPU.
- Cytochrome c sample, plus everything from v1.0 (global/local/semi-global, banded whole-genome alignment, affine gaps, the 3D structure viewer, dot plot, and more).