REDCRAFT is an open-source software tool for determining a protein's structure using residual dipolar couplings (RDCs). It allows simultaneous determination of a protein's structure and dynamics. Its effectiveness has been demonstrated on both synthetic and experimental data. REDCRAFT contains stages that allow the incorporation of user-specified dihedral angle constraints, such as those produced by TALOS or a restriction to specific regions of Ramachandran space. It is robust with respect to noise and missing data. The program is highly efficient and can produce a structure for an 80-residue protein within minutes.
To get started, refer to the REDCRAFT Documentation Online, or you may refer directly to the documentation in the docs/ folder here.