You can get the transpose of a 2-d matrix by hitting it with a matrix like {{0, 1},{1, 0}}.
{{0, 1},{1, 0}}
So Transpose[{{2, 4},{6, 8}}] == {{2, 4},{6, 8}} . {{0, 1},{1, 0}}. It has the effect of turning rows into columns.
Transpose[{{2, 4},{6, 8}}] == {{2, 4},{6, 8}} . {{0, 1},{1, 0}}
If you calculated the determinant of that special matrix (call it S) of 1's and 0's, you'd find that it's determinant is always going to be 1.
S
Since Det[A . B] == Det[A] Det[B], you know that Det[Transpose[A]] == Det[A] Det[S] == Det[A]
Det[A . B] == Det[A] Det[B]
Det[Transpose[A]] == Det[A] Det[S] == Det[A]
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