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v0.1.2: Correctness fixes for the ClinVar significance filter, dual-callset frequency rows, and the LOEUF interval render

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@cyanheads cyanheads released this 28 Jun 04:40
4522d61

Correctness fixes for the ClinVar significance filter, dual-callset frequency rows, and the LOEUF interval render

Fixed:

  • gnomad_search_clinvarclinical_significance enforced post-fetch; the NCBI field tag leaked non-matching classifications, and the whole-word match now composes with min_review_stars (#2)
  • gnomad_list_gene_variantsexome|genome rows report joint AN (sum across callsets) and joint AF (recomputed from ac/an); max_af filters the joint frequency (#3)
  • gnomad_get_gene_constraintcontent[] LOEUF interval upper bound renders oe_lof_upper, not the oe_lof point estimate (#5)

94 tests pass; bun run devcheck clean.