NODDI Lifespan dMRI (Chang & Mukherjee, 2015)
Diffusion MRI from 67 healthy controls (ages 7–63 years) to study white-matter maturation with NODDI (neurite orientation dispersion and density imaging), alongside standard DTI metrics. The release includes multi-shell HARDI (two shells), single-shell DTI, and T1-weighted anatomical images suitable for ROI- and voxel-wise analyses of neurite density (ND), orientation dispersion (OD), and conventional diffusion indices. Subsets include test-retest sessions for reliability assessment. Findings reported in the companion article show ND rising with a logarithmic pattern across childhood to adulthood, OD increasing exponentially later in life, and NODDI measures predicting age more specifically than DTI.
License
Use is governed by the dataset’s UCSF Datashare Data Use Agreement (see Dryad record).
Citation
Chang, Y., & Mukherjee, P. (2015). NODDI-PLOS-ONE-Chang et al 2015 [Data set]. Dryad. https://doi.org/10.7272/Q6D798BD
Primary article: PLOS ONE — Neurite orientation dispersion and density imaging of brain development across the lifespan (2015).
Source
https://doi.org/10.7272/Q6D798BD
Repository: Dryad (Published Mar 2, 2015)
Dataset details
- Participants: 67 healthy controls, 7–63 years; includes test-retest subsets.
- Modalities:
- DTI: single-shell diffusion (b≈1000 s/mm²).
- HARDI (×2): multi-shell diffusion for NODDI modeling.
- Anatomical: T1-weighted MRI.
- Intended uses: lifespan modeling of ND/OD, age prediction, reliability benchmarking, comparison of NODDI vs. DTI.
Suggested acknowledgement
Please cite the Dryad dataset DOI above and the associated PLOS ONE article when using these data.
Keywords
NODDI • Diffusion MRI • DTI • Lifespan • White matter • Development • Test–retest